ARP90353-61 [Polyclonal Antibody]
ATPBD3 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human ATPBD3
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   90353
Swiss Prot:   Q7Z7A3
Synonyms:   ATP binding domain 3, ATP-binding domain-containing protein 3, ATPBD3, Cancer-associated gene protein, cancer-associated protein, CTU1, Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1, cytosolic thiouridylase subunit 1 homo
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   ATPBD3 Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Belongs to the ttcA family.
Caculated MW:   36 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information