Species: | Rabbit |
Applications: | WB IF ICC |
Immunogen Range: | A synthetic peptide derived from human COX42 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 84701 |
Swiss Prot: | Q96KJ9 |
Synonyms: | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial [Precursor], EC 1.9.3.1, Cytochrome c oxidase subunit IV isoform 2, COX IV-2, COX4L2, COX42 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation |
Caculated MW: | 20 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse, Rat |