ARP80781-62 [Polyclonal Antibody]
Collagen XVIIIalpha 1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC IF ICC
Immunogen Range:   A synthetic peptide derived from human Collagen XVIIIalpha 1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   80781
Swiss Prot:   P39060
Synonyms:   Collagen alpha-1(XVIII) chain [Precursor], Endostatin, COIA1
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Three transcripts have been identified for this gene.
Caculated MW:   178 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information