ARP10013-62
[Polyclonal Antibody]
HDAC6 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB IHC |
| Immunogen Range: |
A synthetic peptide derived from human HDAC6 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
10013 |
| Swiss Prot: |
Q9UBN7 |
| Synonyms: |
HD6, HDA6, Histone deacetylase 6, JM21 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. |
| Caculated MW: |
135 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:200
|
| Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!