Species: | Rabbit |
Applications: | IHC IF ICC |
Immunogen Range: | A synthetic peptide derived from human STEAP4 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 79689 |
Swiss Prot: | Q687X5 |
Synonyms: | DKFZp666D049, FLJ23153, Metalloreductase STEAP4, six transmembrane prostate protein 2, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, STAMP2, STEA4, STEAP family member 4, STEAP4, TIARP, TNFAIP9, Tumor necrosis |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | STEAP4 Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Play a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses. Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation. Belongs to the STEAP family. |
Caculated MW: | 51 kDa |
Observed MW: | Refer to Figures |
Applications: |
IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human |