ARPF076-61 [Polyclonal Antibody]
AP-2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide derived from human AP-2
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   7020/7021
Swiss Prot:   P05549/Q92481
Synonyms:   Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2, AP-2 transcription factor, AP-2alpha, AP2-alpha, AP2A, AP2TF, BOFS, FLJ51761, TFAP2, TFAP2A, transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha), Transcript
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   AP-2 alpha Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
Caculated MW:   49 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information