Species: | Rabbit |
Applications: | WB IF ICC |
Immunogen Range: | A synthetic peptide derived from human DUSP16 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 80824 |
Swiss Prot: | Q9BY84 |
Synonyms: | Dual specificity protein phosphatase 16, DUS16, DUSP16, EC 3.1.3.16, EC 3.1.3.48, KIAA1700, MAP kinase phosphatase 7, MAP kinase phosphatase-7, Mitogen-activated protein kinase phosphatase 7, MKP7 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity.[supplied by OMIM] |
Caculated MW: | 73 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse |