YRP11296-01 [Polyclonal Antibody]
HDC2/PHC2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   KLH conjugated synthetic peptide derived from human HDC2/PHC2
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:  
Swiss Prot:  
Synonyms:   Early development regulatory protein 2, hPH2, early development regulator 2 homolog of polyhomeotic 2, early development regulator 2 like, EDR2, MGC163502, mph2, PH2, PHC2, PHC2_HUMAN, polyhomeotic 2, polyhomeotic like 2, Polyhomeotic-like protein 2.
Purification:   Purified by Protein A.
Storage:   Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Background:   Early development regulatory protein 2;hPH2;early development regulator 2 (homolog of polyhomeotic 2);Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development. PHC2 (polyhomeotic-like protein 2), also known as early development regulatory protein 2, is an 858 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Phosphorylated upon DNA damage, PHC2 contains one SAM (sterile alpha motif) domain and one FCS-type zinc finger.
Caculated MW:   /
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information