ARP25816-61 [Polyclonal Antibody]
TFIP8 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF ICC
Immunogen Range:   A synthetic peptide derived from human TFIP8
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   25816
Swiss Prot:   O95379
Synonyms:   GG2-1, Head and neck tumor and metastasis-related protein, MDC-3.13, NDED, NF-kappa-B-inducible DED-containing protein, SCC-S2, SCCS2, TFIP8, TNF alpha-induced protein 8, TNF-induced protein GG2-1, TNFAIP8, Tumor necrosis factor alpha-induced protein 8, t
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   TNFAIP8 Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Belongs to the TNFAIP8 family. Induced by nuclear factor-KB (NF-KB) and TNF. Induction by TNF depends upon activation of NF-KB.
Caculated MW:   23 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information