ARP540-61 [Polyclonal Antibody]
ATP7B Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC IF ICC
Immunogen Range:   A synthetic peptide derived from human ATP7B
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   540
Swiss Prot:   P35670
Synonyms:   ATP7B, ATPase, Cu(2+)- transporting, beta polypeptide, ATPase, Cu++ transporting, beta polypeptide, Copper pump 2, Copper-transporting ATPase 2, PWD, WC1, WD, Wilson disease-associated protein, WND, WND/140 kDa
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a polypeptide that acts as a membrane copper-transport protein. Defects in this gene are the cause of Wilson disease (WD). WD is an autosomal recessive disorder of copper metabolism in which copper cannot be incorporated into ceruloplasmin in liver, and cannot be excreted from the liver into the bile. Alternatively spliced transcript variants encoding different isoforms have been identified.
Caculated MW:   157 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information