
| Species: | Rabbit |
| Applications: | WB IF ICC |
| Immunogen Range: | A synthetic peptide derived from human MUTYH |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 4595 |
| Swiss Prot: | Q9UIF7 |
| Synonyms: | A/G-specific adenine DNA glycosylase, CYP2C, hMYH, MGC4416, MutY homolog, mutY homolog (E. coli), MUTYH, MYH |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | MUTYH Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2- OH-A DNA glycosylase activities. Belongs to the Nth/MutY family. 6 isoforms of the human protein are produced by alternative splicing. |
| Caculated MW: | 60 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:3000 IF 1:100-1:500 ICC 1:100-1:500 |
| Reacitivity: | Human, Mouse, Rat |