ARP10482-61 [Polyclonal Antibody]
NXF1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human NXF1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   10482
Swiss Prot:   Q9UBU9
Synonyms:   DKFZp667O0311, MEX67, mRNA export factor TAP, Nuclear RNA export factor 1, NXF1, TAP, tip associating protein, Tip-associated protein, Tip-associating protein
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   NXF1 Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with THOC4 and THOC5. Belongs to the NXF family. Heterodimer with NXT1. Interacts (via NTF2 domain) with NXT1. The formation of NXF1/NXT1 heterodimers is required for the NXF1-mediated nuclear mRNA export. Interacts with NXT2, E1B-AP5, RAE1, THOC4 and with several nucleoporins. Is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, RENT1, RENT2, RENT3A, RENT3B, THOC4 and/or REFBP2. Found in a mRNA complex with RENT3A and RENT3B. Interacts with FYTTD1/UIF, EIF4A3, NUPL2 and THOC5. Interacts with Saimiriine herpesvirus 2 TIP protein
Caculated MW:   70 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:3000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information