ARP7030-61 [Polyclonal Antibody]
TFE3 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide derived from human TFE3
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   7030
Swiss Prot:   P19532
Synonyms:   class E basic helix-loop-helix protein 33, DKFZp761J1810, Putative uncharacterized protein DKFZp761J1810, RCCP2, TFE3, TFEA, transcription factor binding to IGHM enhancer 3
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   TFE3 Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer.
Caculated MW:   62 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:3000
IHC 1:50-1:200
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information