ARP7030-61
[Polyclonal Antibody]
TFE3 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptide derived from human TFE3 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
7030 |
Swiss Prot: |
P19532 |
Synonyms: |
class E basic helix-loop-helix protein 33, DKFZp761J1810, Putative uncharacterized protein DKFZp761J1810, RCCP2, TFE3, TFEA, transcription factor binding to IGHM enhancer 3 |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
TFE3 Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. |
Caculated MW: |
62 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:3000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!