ARP326-61
[Polyclonal Antibody]
AIRE Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IF ICC |
| Immunogen Range: | A synthetic peptide derived from human AIRE |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 326 |
| Swiss Prot: | O43918 |
| Synonyms: | AIRE, AIRE1, APECED, APECED protein, APS1, APSI, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator, PGA1 |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | AIRE Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment; the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes. Binds to chromatin and interacts selectively with histone H3 that is not methylated at 'Lys-4', not phosphorylated at 'Thr-3' and not methylated at 'Arg-2'. |
| Caculated MW: | 60 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:3000 IF 1:100-1:500 ICC 1:100-1:500 |
| Reacitivity: | Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
