ARP9575-61
[Polyclonal Antibody]
Clock Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptide derived from human Clock |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
9575 |
Swiss Prot: |
O15516 |
Synonyms: |
BHLHE8, circadian locomoter output cycles kaput protein, Circadian locomoter output cycles protein kaput, Class E basic helix-loop-helix protein 8, CLOCK, clock homolog (mouse), hCLOCK, KAT13D, KIAA0334 |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
CLOCK ARNTL/2-CLOCK heterodimers activate E-box element (3'- CACGTG-5') transcription of a number of proteins of the circadian clock. Activates transcription of PER1 and PER2. This transcription is inhibited in a feedback loop by PER and CRY proteins. Has intrinsic histone acetyltransferase activity and this enzymatic function contributes to chromatin-remodeling events implicated in circadian control of gene expression. Acetylates primarily histones H3 and H4. |
Caculated MW: |
95 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:3000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!