ARP23037-61 [Polyclonal Antibody]
PDZD2 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
Species:   Rabbit
Applications:   IHC IF ICC
Immunogen Range:   A synthetic peptide derived from human PDZD2
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   23037
Swiss Prot:   O15018
Synonyms:   PDZ domain-containing protein 2, PDZ domain-containing protein 3, Activated in prostate cancer protein, Processed PDZ domain-containing protein 2, PDZD2, AIPC, KIAA0300, PDZK3
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. Two transcript variants encoding different isoforms have been found for this gene.
Caculated MW:   301 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information