Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A synthetic peptide derived from human TNFSF11 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 8600 |
Swiss Prot: | O14788 |
Synonyms: | CD254, hRANKL2, ODF, OPGL, OPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANKL, receptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, TNF-related activation-induced cytokine, TN |
Purification: | Affinity chromatography |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | TNFSF11 Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. |
Caculated MW: | 40 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:3000 IHC 1:50-1:200 IF 0.180556 |
Reacitivity: | Human, Mouse |