ARP10403-61 [Polyclonal Antibody]
HEC1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF ICC
Immunogen Range:   A synthetic peptide derived from human HEC1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   10403
Swiss Prot:   O14777
Synonyms:   HEC, HEC1, Highly expressed in cancer protein, highly expressed in cancer, rich in leucine heptad repeats, HsHec1, hsNDC80, kinetochore associated 2, Kinetochore protein Hec1, Kinetochore protein NDC80 homolog, Kinetochore-associated protein 2, KNTC2, NDC
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   HEC1 plays an essential role in chromosome segregation by interacting through its coiled-coil domains with several proteins that modulate the G2/M phase. Phosphorylation by Nek2 is essential for faithful chromosome segregation. Required for the recruitment of Mps1 kinase and Mad1/Mad2 complexes to kinetochores.
Caculated MW:   73 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:3000
IF 1:100-1:500
ICC 1:100-1:500
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information