ARP8797-61
[Polyclonal Antibody]
TR10A Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB |
| Immunogen Range: | A synthetic peptide derived from human TR10A |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 8797 |
| Swiss Prot: | O00220 |
| Synonyms: | APO2, CD261, cytotoxic TRAIL receptor, Death receptor 4, DR4, MGC9365, TNF-related apoptosis inducing ligand receptor 1, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TR10A, TRAIL receptor 1, TRAIL-R1, TRAILR-1, TRAILR1, Tumor necrosis fact |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | TRAIL-R1 Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. |
| Caculated MW: | 50 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:3000 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
