ARP7518-61 [Polyclonal Antibody]
XRCC4 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human XRCC4
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   7518
Swiss Prot:   Q13426
Synonyms:   DNA repair protein XRCC4, X-ray repair complementing defective repair in Chinese hamster cells 4, X-ray repair cross complementing protein 4, X-ray repair cross-complementing protein 4, X-ray repair, complementing defective, repair in Chinese hamster, XR
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   XRCC4 Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. Belongs to the XRCC4 family.
Caculated MW:   40 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:3000
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information