ARP7516-61
[Polyclonal Antibody]
XRCC2 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
IHC |
Immunogen Range: |
A synthetic peptide derived from human XRCC2 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
7516 |
Swiss Prot: |
O43543 |
Synonyms: |
DKFZp781P0919, DNA repair protein XRCC2, RAD51-like, X-ray repair complementing defective repair in Chinese hamster cells 2, X-ray repair cross complementing protein 2, X-ray repair cross-complementing protein 2, X-ray repair, complementing defective, rep |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
XRCC2 Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Belongs to the recA family. RAD51 subfamily. Interacts with RAD51D. Part of a BCDX2 complex consisting of RAD51B, RAD51C, RAD51D and XRCC2. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3. In the absence of DNA, XRCC2-RAD51D formed a multimeric ring structure. In the presence of single-stranded DNA, XRCC2-RAD51D formed a filamentous structure. Note: This description may include information from UniProtKB. |
Caculated MW: |
32 kDa |
Observed MW: |
Refer to Figures |
Applications: |
IHC 1:50-1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!