ARP7155-61
[Polyclonal Antibody]
TOP2B Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC |
| Immunogen Range: | A synthetic peptide derived from human TOP2B |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 7155 |
| Swiss Prot: | Q02880 |
| Synonyms: | antigen MLAA-44, DNA topoisomerase 2-beta, DNA topoisomerase II beta, DNA topoisomerase II, 180 kD, DNA topoisomerase II, beta isozyme, TOP2B, top2beta, TOPIIB, topo II beta, topoisomerase (DNA) II beta 180kDa |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | TOP2B Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly ivolved in vitamin D- coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR- mediated transrepression of the CYP27B1 gene. Belongs to the type II topoisomerase family. |
| Caculated MW: | 183 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:3000 IHC 1:50-1:200 |
| Reacitivity: | Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
