ARP10401-61 [Polyclonal Antibody]
PIAS3 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide derived from human PIAS3
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   10401
Swiss Prot:   Q9Y6X2
Synonyms:   E3 SUMO-protein ligase PIAS3, FLJ14651, PIAS3, Protein inhibitor of activated STAT protein 3, protein inhibitor of activated STAT, 3, zinc finger, MIZ-type containing 5, ZMIZ5
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   PIAS3 Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context. Belongs to the PIAS family.
Caculated MW:   68 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:3000
IHC 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information