ARP9063-61 [Polyclonal Antibody]
PIAS2 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human PIAS2
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   9063
Swiss Prot:   O75928
Synonyms:   Androgen receptor-interacting protein 3, ARIP3, DAB2-interacting protein, DIP, E3 SUMO-protein ligase PIAS2, MGC102682, miz, Miz1, Msx-interacting zinc finger protein, Msx-interacting-zinc finger, PIAS-NY protein, PIAS2, PIASX, PIASX-ALPHA, PIASX-BETA, P
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   PIAS2 Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing may vary depending upon the biological context and the PIAS2 isoform studied.
Caculated MW:   68 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:3000
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information