ARP51667-61
[Polyclonal Antibody]
NYREN18 Rabbit Polyclonal Antibody
www.yhsbio.com
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptide derived from human NYREN18 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
51667 |
Swiss Prot: |
Q9Y5A7 |
Synonyms: |
BS4, NEDD8 ultimate buster 1, NEDD8 ultimate buster-1, Negative regulator of ubiquitin-like proteins 1, NUB1, NUB1L, NY-REN-18 antigen, NYREN18, Renal carcinoma antigen NY-REN-18 |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
NYREN18 Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8 and its conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. Induced by beta and gamma interferons. Directly interacts with NEDD8 and PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome. |
Caculated MW: |
70 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:3000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!