ARP51366-61 [Polyclonal Antibody]
EDD Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide derived from human EDD
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   51366
Swiss Prot:   O95071
Synonyms:   DD5, E3 identified by differential display, E3 ubiquitin protein ligase, HECT domain containing, 1, E3 ubiquitin-protein ligase UBR5, E3 ubiquitin-protein ligase, HECT domain-containing 1, EDD, EDD1, FLJ11310, hHYD, HYD, Hyperplastic discs protein homolog
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   UBR5 E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Caculated MW:   309 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:3000
IHC 1:50-1:200
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information