
| Species: | Rabbit |
| Applications: | WB IF ICC |
| Immunogen Range: | A synthetic peptide derived from human AOS1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 10055 |
| Swiss Prot: | Q9UBE0 |
| Synonyms: | activator of SUMO1, AOS1, FLJ3091, HSPC140, SAE1, sentrin/SUMO-activating protein AOS1, SUA1, SUMO-1 activating enzyme E1 N subunit, SUMO-1 activating enzyme subunit 1, SUMO-activating enzyme subunit 1, SUMO1 activating enzyme subunit 1, Ubiquitin-like 1 |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | UBLE1A The dimeric enzyme acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2. Belongs to the ubiquitin-activating E1 family. Heterodimer of SAE1 and SAE2. The complex binds SUMO proteins via SAE2. |
| Caculated MW: | 38 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:3000 IF 1:100-1:500 ICC 1:100-1:500 |
| Reacitivity: | Human, Mouse, Rat |