ARP6016-61 [Polyclonal Antibody]
RIT1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human RIT1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   6016
Swiss Prot:   Q92963
Synonyms:   GTP-binding protein Rit1, GTP-binding protein Roc1, MGC125864, MGC125865, Ras-like protein expressed in many tissues, Ras-like without CAAX 1, Ras-like without CAAX protein 1, RIBB, Ric-like, expressed in many tissues, RIT, RIT1, ROC1
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   RIT1 Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Belongs to the small GTPase superfamily. Ras family. Interacts with MLLT4, the C-terminal domain of RALGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form.
Caculated MW:   25 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:3000
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information