ARP6016-61
[Polyclonal Antibody]
RIT1 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide derived from human RIT1 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
6016 |
| Swiss Prot: |
Q92963 |
| Synonyms: |
GTP-binding protein Rit1, GTP-binding protein Roc1, MGC125864, MGC125865, Ras-like protein expressed in many tissues, Ras-like without CAAX 1, Ras-like without CAAX protein 1, RIBB, Ric-like, expressed in many tissues, RIT, RIT1, ROC1 |
| Purification: |
Affinity chromatography |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
RIT1 Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Belongs to the small GTPase superfamily. Ras family. Interacts with MLLT4, the C-terminal domain of RALGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form. |
| Caculated MW: |
25 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:3000
|
| Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!