ARP5663-61
[Polyclonal Antibody]
Presenilin 1 Rabbit Polyclonal Antibody
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support@yhsbio.com
+86-21-54651191
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Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC |
| Immunogen Range: | A synthetic peptide derived from human Presenilin 1 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 5663 |
| Swiss Prot: | P49768 |
| Synonyms: | AD3, FAD, presenilin 1, Presenilin-1, Presenilin-1 CTF subunit, Presenilin-1 CTF12, Presenilin-1 NTF subunit, Protein S182, PS-1, PS1, PS1-CTF12, PSEN1, PSN1, PSNL1, S182 |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | PSEN1 probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Regulates epithelial- cadherin function. |
| Caculated MW: | 60 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:3000 IHC 1:50-1:200 |
| Reacitivity: | Human |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
