ARP4824-61 [Polyclonal Antibody]
NKX3.1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   IHC
Immunogen Range:   A synthetic peptide derived from human NKX3.1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   4824
Swiss Prot:   Q99801
Synonyms:   BAPX2, Homeobox protein NK-3 homolog A, Homeobox protein Nkx-3.1, NK homeobox, family 3, A, NK3 homeobox 1, NK3 transcription factor homolog A, NK3 transcription factor related, locus 1, NKX3, NKX3-1, NKX3.1, NKX31, NKX3A
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   NKX3-1 Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. Interacts with serum response factor (SRF).
Caculated MW:   38 kDa
Observed MW:   Refer to Figures
Applications:   IHC 1:50-1:200
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information