ARP4318-61
[Polyclonal Antibody]
MMP9 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptide derived from human MMP9 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
4318 |
Swiss Prot: |
P14780 |
Synonyms: |
67 kDa matrix metalloproteinase-9, 82 kDa matrix metalloproteinase-9, 92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, Gelatinase B, GELB, macrophage gelatinase, MANDP2, matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collage |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
MMP9 May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Belongs to the peptidase M10A family. Activated by 4-aminophenylmercuric acetate and phorbol ester. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1. |
Caculated MW: |
78 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:3000 IHC 1:50-1:200
|
Reacitivity: |
Human |
For research use only. Not intended for diagnostic or therapeutic use!