Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A synthetic peptide derived from human MCL1 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 4170 |
Swiss Prot: | Q07820 |
Synonyms: | Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, Bcl2-L-3, BCL2L3, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1, MCL1, mcl1/EAT, MCL1L, MCL1S, MGC104264, MGC1839, myeloid cell leukemia ES, myeloid cell leukemia sequence 1 |
Purification: | Affinity chromatography |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | MCL1 a myeloid cell leukemia protein of the Bcl-2 family of proteins. Two alternatively spliced transcripts encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. |
Caculated MW: | 32,37 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:3000 IHC 1:50-1:200 IF 0.180556 |
Reacitivity: | Human, Mouse, Rat |