Species: | Rabbit |
Applications: | WB IHC IF ICC |
Immunogen Range: | A synthetic peptide derived from human iNOS |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 4843 |
Swiss Prot: | P35228 |
Synonyms: | HEP-NOS, Hepatocyte NOS, Inducible NO synthase, Inducible NOS, iNOS, nitric oxide synthase 2, inducible, nitric oxide synthase 2A (inducible, hepatocytes), Nitric oxide synthase, inducible, nitric oxide synthase, macrophage, NOS, NOS type II, NOS, type II |
Purification: | Affinity chromatography |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | iNOS Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Belongs to the NOS family. Induced by endotoxins and cytokines. Induced by interferon gamma acting synergistically with lipopolysaccharide, tumor necrosis factor alpha or interleukin-1 beta. Homodimer. Binds SLC9A3R1. 2 isoforms of the human protein are produced by alternative splicing. |
Caculated MW: | 130 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:3000 IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human |