ARP8533-61
[Polyclonal Antibody]
COPS3 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IF ICC |
| Immunogen Range: | A synthetic peptide derived from human COPS3 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 8533 |
| Swiss Prot: | Q9UNS2 |
| Synonyms: | COP9 complex subunit 3, COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis), COP9 signalosome complex subunit 3, COPS3, CSN3, JAB1-containing signalosome subunit 3, SGN3, Signalosome subunit 3 |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | COPS3 Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. |
| Caculated MW: | 47 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:3000 IF 1:100-1:500 ICC 1:100-1:500 |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
