ARPF080-61
[Polyclonal Antibody]
Granzyme B Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC |
| Immunogen Range: | A synthetic peptide derived from human Granzyme B |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 2999/3002 |
| Swiss Prot: | P20718/P10144 |
| Synonyms: | C11, Cathepsin G-like 1, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA-1, CTLA1, CTSGL1, cytotoxic serine protease B, Cytotoxic T-lymphocyte proteinase 2, fragmentin 2, Fragmentin-2, GRAB, Granzyme B, granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serin |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | GZMB This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. Belongs to the peptidase S1 family. Granzyme subfamily. Induced by staphylococcal enterotoxin A (SEA) in peripheral blood leukocytes. |
| Caculated MW: | 28 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:3000 IHC 1:50-1:200 |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
