ARP2263-61
[Polyclonal Antibody]
FGFR2 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptide derived from human FGFR2 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
2263 |
Swiss Prot: |
P21802 |
Synonyms: |
bacteria-expressed kinase, BEK, BEK fibroblast growth factor receptor, BFR-1, CD332, CEK3, CFD1, ECT1, FGF receptor, FGFR-2, FGFR2, Fibroblast growth factor receptor 2, FLJ98662, hydroxyaryl-protein kinase, JWS, K-sam, Keratinocyte growth factor receptor |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
FGFR2 a receptor tyrosine kinase of the highly-conserved FGFR family that binds fibroblast growth factor (FGF). Mutations are associated with many craniosynostotic syndromes and bone malformations. Mutations cause syndromes with defects in facial and limb development, including Crouzon syndrome, Beare-Stevenson cutis gyrata syndrome, Pfeiffer syndrome, Apert syndrome, and Jackson-Weiss syndrome. Somatic mutations seen in gastric cancer. Amplified in gastric, breast and some B cell cancers, but deleted in glioblastoma Twenty splice-variant isoforms have been described. Note: This description may include information from UniProtKB. |
Caculated MW: |
92 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:3000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!