ARP2067-61
[Polyclonal Antibody]
ERCC1 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IHC |
Immunogen Range: |
A synthetic peptide derived from human ERCC1 |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
2067 |
Swiss Prot: |
P07992 |
Synonyms: |
COFS4, DNA excision repair protein ERCC-1, ERCC1, excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), UV20 |
Purification: |
Affinity chromatography |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
ERCC1 a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA excision repair. Belongs to the ERCC1/RAD10/SWI10 family. Heterodimer composed of ERCC1 and XPF/ERRC4. Defects in ERCC1 are the cause of cerebro-oculo-facio-skeletal syndrome type 4, a degenerative autosomal recessive disorder of prenatal onset affecting the brain, eye and spinal cord. |
Caculated MW: |
36 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:3000 IHC 1:50-1:200
|
Reacitivity: |
Human, Mouse |
For research use only. Not intended for diagnostic or therapeutic use!