ARP8291-61 [Polyclonal Antibody]
Dysferlin Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human Dysferlin
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   8291
Swiss Prot:   O75923
Synonyms:   DYSF, Dysferlin, dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive), dystrophy-associated fer-1-like 1, Dystrophy-associated fer-1-like protein, Fer-1-like protein 1, FER1L1, FLJ00175, FLJ90168, LGMD2B
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   DYSF Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Belongs to the ferlin family. Interacts with CACNA1S. Interacts with ANXA1; the interaction is Ca(2+)- and injury state-dependent.
Caculated MW:   240 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:3000
Reacitivity:   Human, Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information