Species: | Rabbit |
Applications: | IHC IF ICC |
Immunogen Range: | A synthetic peptide derived from human Collagen I |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 1278 |
Swiss Prot: | P08123 |
Synonyms: | Collagen alpha-2(I) chain [Precursor], Alpha-2 type I collagen, CO1A2 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | This gene encodes one of the chains for type I collagen, the fibrillar collagen found in most connective tissues. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for alpha-1 type I collagen since alpha-2 is less abundant. Multiple messages for this gene result from multiple polyadenylation signals, a feature shared by most of the other collagen genes. |
Caculated MW: | 129 kDa |
Observed MW: | Refer to Figures |
Applications: |
IHC 1:50-1:200 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Mouse, Rat |