ARP9076-61 [Polyclonal Antibody]
Claudin 1 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide derived from human Claudin 1
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   9076
Swiss Prot:   O95832
Synonyms:   claudin 1, Claudin-1, CLD1, CLDN1, ILVASC, SEMP1, Senescence-associated epithelial membrane protein, senescence-associated epithelial membrane protein 1
Purification:   Affinity chromatography
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   claudin 1 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Acts as a co- receptor for HCV entry into hepatic cells. Belongs to the claudin family. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL. May interact with HCV E1 and E2 proteins.
Caculated MW:   22 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:3000
IHC 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information