ARP581-62
[Polyclonal Antibody]
Bax Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | A synthetic peptide derived from human Bax |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 581 |
| Swiss Prot: | Q07812 |
| Synonyms: | Apoptosis regulator BAX, BAX, Bcl-2-like protein 4, BCL2-associated X protein, Bcl2-L-4, BCL2L4 |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | Bax Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Induces the release of cytochrome c, activation of CASP3, and thereby apoptosis. Belongs to the Bcl-2 family. Homodimer. Forms heterodimers with BCL2, E1B 19K protein, BCL2L1 isoform Bcl-X(L), MCL1 and A1. Interacts with SH3GLB1 and HN. Interacts with SFN and YWHAZ; the interaction occurs in the cytoplasm. Under stress conditions, JNK-mediated phosphorylation of SFN and YWHAZ, releases BAX to mitochondria. Isoform Sigma interacts with BCL2A1 and BCL2L1 isoform Bcl-X(L). 8 isoforms of the human protein are produced by alternative splicing. |
| Caculated MW: | 21 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:3000 IHC 1:50-1:200 IF 0.180556 |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
