ARP5884-61
[Polyclonal Antibody]
RAD17 Rabbit Polyclonal Antibody
www.yhsbio.com
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
market@yhsbio.com
support@yhsbio.com
+86-21-54651191
Room 703,Building 6,333# Guiping
Rd.,Xuhui District,Shanghai,China
DATASHEET
| Species: | Rabbit |
| Applications: | WB |
| Immunogen Range: | A synthetic peptide derived from human RAD17 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 5884 |
| Swiss Prot: | O75943 |
| Synonyms: | CCYC, cell cycle checkpoint protein (RAD17), Cell cycle checkpoint protein RAD17, FLJ41520, hRad17, R24L, RAD1 homolog, RAD17, RAD17 homolog (S. pombe), Rad17-like protein, RAD17SP, RAD24, RF-C activator 1 homolog, RF-C/activator 1 homolog |
| Purification: | Affinity chromatography |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | Rad17 a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. Shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. Binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. Phosphorylated and activated after DNA damage, inducing cell cycle G2 arrest. Eight alternatively spliced variants have been reported. |
| Caculated MW: | 77 kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:3000 |
| Reacitivity: | Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!
Additional information
