Species: | Rabbit |
Applications: | WB IF ICC |
Immunogen Range: | A synthetic peptide derived from human EPHA2/3/4 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 1969 |
Swiss Prot: | P29317/P29320/P54764 |
Synonyms: | ARCC2, ECK, EPH receptor A2, EPHA2, ephrin receptor EphA2, Ephrin type-A receptor 2, Epithelial cell kinase, epithelial cell receptor protein tyrosine kinase, protein tyrosine kinase, soluble EPHA2 variant 1, Tyrosine-protein kinase receptor ECK |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | EphA2 a receptor tyrosine kinase. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 AND -A5. The Eph receptor tyrosine kinase family, the largest in the tyrosine kinase group, has fourteen members. They bind membrane-anchored ligands, ephrins, at sites of cell-cell contact, regulating the repulsion and adhesion of cells that underlie the establishment, maintenance, and remodeling of patterns of cellular organization. Eph signals are particularly important in regulating cell adhesion and cell migration during development, axon guidance, homeostasis and disease. |
Caculated MW: | 130 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IF 1:100-1:500 ICC 1:100-1:500 |
Reacitivity: | Human, Rat |