ARP2060P-61
[Polyclonal Antibody]
Phospho-EPS15-Tyr849 Rabbit Polyclonal Antibody
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DATASHEET
| Species: |
Rabbit |
| Applications: |
WB |
| Immunogen Range: |
A synthetic peptide derived from human EPS15 around the phosphorylation site of Tyrosine 849 |
| Clonality: |
Polyclonal Antibody |
| Isotype: |
IgG |
| GENE ID: |
2060 |
| Swiss Prot: |
P42566 |
| Synonyms: |
AF-1p protein, AF1P, EP15, epidermal growth factor receptor pathway substrate 15 (AF1p), epidermal growth factor receptor substrate 15 |
| Purification: |
Affinity purification |
| Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: |
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
| Caculated MW: |
98 kDa |
| Observed MW: |
Refer to Figures |
| Applications: |
WB 1:500-1:2000
|
| Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!