ARP2060P-61 [Polyclonal Antibody]
Phospho-EPS15-Tyr849 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A synthetic peptide derived from human EPS15 around the phosphorylation site of Tyrosine 849
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   2060
Swiss Prot:   P42566
Synonyms:   AF-1p protein, AF1P, EP15, epidermal growth factor receptor pathway substrate 15 (AF1p), epidermal growth factor receptor substrate 15
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Caculated MW:   98 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information