ARP5914P-61 [Polyclonal Antibody]
Phospho-Retinoic Acid Receptor alpha-Ser77 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC
Immunogen Range:   A synthetic peptide derived from human Retinoic Acid Receptor alpha around the phosphorylation site of Sersine 77
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   5914
Swiss Prot:   P10276
Synonyms:   NR1B1, RAR-alpha, Retinoic acid receptor alpha, retinoic acid receptor, alpha, RRA
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   RARA is a receptor for retinoic acid, a potent mammalian morphogen and teratogen that has profound effects on vertebrate development. RARA is a member of the nuclear receptor superfamily. Controls cell function by directly regulating gene expression. Its phosphorylation is crucial for transcriptional activity. Aberrations involving RARA may be a cause of acute promyelocytic leukemia. Two splice-variant isoforms have been described.
Caculated MW:   45 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:200
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information