Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A phospho specific peptide corresponding to residues surrounding S216 of human CDC25C |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 995 |
Swiss Prot: | P30307 |
Synonyms: | CDC25, PPP1R60 |
Purification: | Affinity purification |
Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: | This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. |
Caculated MW: | 80 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200 |
Reacitivity: | Human |