ARP995P-01 [Polyclonal Antibody]
Phospho-CDC25C-Ser216 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A phospho specific peptide corresponding to residues surrounding S216 of human CDC25C
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   995
Swiss Prot:   P30307
Synonyms:   CDC25, PPP1R60
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Caculated MW:   80 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IHC 1:50-1:100
IF 1:100-1:200
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information