ARP695P-01
[Polyclonal Antibody]
Phospho-BTK-Tyr223 Rabbit Polyclonal Antibody
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Species: |
Rabbit |
Applications: |
WB IF |
Immunogen Range: |
A phospho specific peptide corresponding to residues surrounding Y223 of human Btk |
Clonality: |
Polyclonal Antibody |
Isotype: |
IgG |
GENE ID: |
695 |
Swiss Prot: |
Q06187 |
Synonyms: |
AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK1 |
Purification: |
Affinity purification |
Storage: |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Background: |
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Caculated MW: |
76 kDa |
Observed MW: |
Refer to Figures |
Applications: |
WB 1:500-1:2000 IF 1:20-1:100
|
Reacitivity: |
Human, Mouse, Rat |
For research use only. Not intended for diagnostic or therapeutic use!