ARP695P-01 [Polyclonal Antibody]
Phospho-BTK-Tyr223 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IF
Immunogen Range:   A phospho specific peptide corresponding to residues surrounding Y223 of human Btk
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   695
Swiss Prot:   Q06187
Synonyms:   AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK1
Purification:   Affinity purification
Storage:   Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Caculated MW:   76 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500-1:2000
IF 1:20-1:100
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information