
| Species: | Rabbit |
| Applications: | WB IHC ICC |
| Immunogen Range: | A phospho specific peptide corresponding to residues surrounding serine 2448 of human MTOR/FRAP |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 2475 |
| Swiss Prot: | P42345 |
| Synonyms: | FRAP, FRAP1, FRAP2, RAFT1, RAPT1 |
| Purification: | Affinity purification |
| Storage: | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Background: | The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq |
| Caculated MW: | / |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500-1:2000 IHC 1:50-1:100 ICC 1:50-1:200 |
| Reacitivity: | Human |