Species: | Rabbit |
Applications: | WB IHC IF |
Immunogen Range: | A phospho specific peptide corresponding to residues surrounding T53 of_+E_human ATF2 |
Clonality: | Polyclonal Antibody |
Isotype: | IgG |
GENE ID: | 1386 |
Swiss Prot: | P15336 |
Synonyms: | CREB2, CRE-BP1 |
Purification: | Affinity purification |
Storage: | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background: | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. |
Caculated MW: | 65-75 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
Reacitivity: | Human, Mouse, Rat |