ARP1386P-01 [Polyclonal Antibody]
Phospho-ATF2-Thr53 Rabbit Polyclonal Antibody
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Species:   Rabbit
Applications:   WB IHC IF
Immunogen Range:   A phospho specific peptide corresponding to residues surrounding T53 of_+E_human ATF2
Clonality:   Polyclonal Antibody
Isotype:   IgG
GENE ID:   1386
Swiss Prot:   P15336
Synonyms:   CREB2, CRE-BP1
Purification:   Affinity purification
Storage:   Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background:   This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene.
Caculated MW:   65-75 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Reacitivity:   Human, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information