
| Species: | Rabbit |
| Applications: | WB IHC IF |
| Immunogen Range: | A recombinant protein of human RUNX3 |
| Clonality: | Polyclonal Antibody |
| Isotype: | IgG |
| GENE ID: | 864 |
| Swiss Prot: | Q13761 |
| Synonyms: | AML2, CBFA3, PEBP2aC |
| Purification: | Affinity purification |
| Storage: | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background: | This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Caculated MW: | 44kDa |
| Observed MW: | Refer to Figures |
| Applications: |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100 |
| Reacitivity: | Human |